Hesperidin Lowered Blood Pressure, Reduced Inflammation in Type 2 Diabetes
People with diabetes often have circulatory and inflammatory conditions. In this study, 64 men and women with type 2 diabetes took 500 mg of hesperidin per day, or a placebo.
After six weeks, while the placebo group had not changed compared to the start of the study, those taking hesperidin saw systolic blood pressure decline to 119 from 122.7 mmHg. Doctors also measured average arterial blood pressure, which declined to 91.8 from 94.2 mmHg.
Measuring inflammation, levels of interleukin-6, an inflammatory marker, decreased to 7.4 from 8.3, and another marker, high-sensitivity C-reactive protein, dropped by 42 percent to 1.1 from 1.9. Meanwhile, total antioxidant capacity increased to 0.82 from 0.74.
Discussing the findings, doctors said the bioflavonoid hesperidin, primarily found in citrus fruits, may help blood vessels function better and reduce inflammation in type 2 diabetes.
(Reference: Phytotherapy Research; 2018, Published Online)